| home Friday, February 16 | William & Mary | Clemson, S.C. | 4:00 PM | W, 5 - 4 | |
| home Saturday, February 17 | William & Mary | Clemson, S.C. | 2:00 PM | W, 7 - 6 | |
| home Sunday, February 18 | William & Mary | Clemson, S.C. | 3:00 PM | W, 2 - 1 | |
| home Tuesday, February 20 | Furman | Clemson, S.C. | 4:00 PM | W, 12 - 4 | |
| home Friday, February 23 | Dallas Baptist | Clemson, S.C. | 4:00 PM | W, 12 - 1 | |
| home Saturday, February 24 | Dallas Baptist | Clemson, S.C. | 1:00 PM | W, 3 - 2 | |
| home Saturday, February 24 | Dallas Baptist | Clemson, S.C. | 1:00 PM | W, 9 - 1 | |
| home Tuesday, February 27 | Winthrop | Clemson, S.C. | 4:00 PM | W, 9 - 8 (10) | |
| away Friday, March 02 | South Carolina | Columbia, S.C. | 7:00 PM | L, 2 - 3 | |
| neutral Saturday, March 03 | South Carolina | Greenville, S.C. | 3:00 PM | W, 5 - 1 | |
| home Sunday, March 04 | South Carolina | Clemson, S.C. | 2:00 PM | W, 8 - 7 | |
| home Tuesday, March 06 | Wofford | Clemson, S.C. | 6:30 PM | W, 6 - 3 | |
| neutral Wednesday, March 07 | Michigan State | Greenville, S.C. | 7:00 PM | W, 9 - 7 | |
| home Friday, March 09 | Georgia Tech * | Clemson, S.C. | 6:30 PM | W, 3 - 2 | |
| home Saturday, March 10 | Georgia Tech * | Clemson, S.C. | 1:00 PM | W, 13 - 2 | |
| home Saturday, March 10 | Georgia Tech * | Clemson, S.C. | 4:00 PM | W, 7 - 3 | |
| home Tuesday, March 13 | Charleston Southern | Clemson, S.C. | 6:30 PM | W, 5 - 0 | |
| home Friday, March 16 | North Carolina State * | Clemson, S.C. | 6:30 PM | L, 0 - 4 | |
| home Saturday, March 17 | North Carolina State * | Clemson, S.C. | 4:00 PM | L, 1 - 6 | |
| home Sunday, March 18 | North Carolina State * | Clemson, S.C. | 1:00 PM | L, 4 - 5 | |
| away Tuesday, March 20 | Coastal Carolina | Conway, S.C. | 6:00 PM | L, 5 - 9 | |
| away Friday, March 23 | Louisville * | Louisville, Ky. | 6:00 PM | W, 3 - 1 | |
| away Sunday, March 25 | Louisville * | Louisville, Ky. | 1:00 PM | W, 4 - 3 | |
| away Sunday, March 25 | Louisville * | Louisville, Ky. | 1:00 PM | L, 1 - 5 | |
| away Tuesday, March 27 | Furman | Greenville, S.C. (Fluor Field) | 6:00 PM | W, 10 - 5 | |
| home Thursday, March 29 | Boston College * | Clemson, S.C. | 6:30 PM | W, 10 - 2 | |
| home Friday, March 30 | Boston College * | Clemson, S.C. | 6:30 PM | W, 9 - 4 | |
| home Saturday, March 31 | Boston College * | Clemson, S.C. | 2:00 PM | W, 8 - 3 | |
| home Tuesday, April 03 | Coastal Carolina | Clemson, S.C. | 6:30 PM | W, 6 - 1 | |
| away Saturday, April 07 | Notre Dame * | Notre Dame, Ind. | 6:05 PM | L, 2 - 5 | |
| away Sunday, April 08 | Notre Dame * | Notre Dame, Ind. | 2:05 PM | W, 6 - 3 | |
| away Sunday, April 08 | Notre Dame * | Notre Dame, Ind. | 1:05 PM | W, 5 - 2 | |
| neutral Tuesday, April 10 | Georgia | North Augusta, S.C. | 6:30 PM | L, 3 - 6 | |
| home Friday, April 13 | Miami FL * | Clemson, S.C. | 6:30 PM | L, 11 - 12 (12) | |
| home Saturday, April 14 | Miami FL * | Clemson, S.C. | 5:00 PM | L, 1 - 6 | |
| home Saturday, April 14 | Miami FL * | Clemson, S.C. | 1:00 PM | W, 8 - 3 | |
| away Tuesday, April 17 | Georgia | Athens, Ga. | 7:00 PM | L, 1 - 6 | |
| away Friday, April 20 | Wake Forest * | Winston-Salem, N.C. | 6:00 PM | W, 7 - 5 | |
| away Saturday, April 21 | Wake Forest * | Winston-Salem, N.C. | 4:00 PM | W, 4 - 3 | |
| away Sunday, April 22 | Wake Forest * | Winston-Salem, N.C. | 1:00 PM | W, 9 - 4 | |
| home Tuesday, April 24 | Kennesaw State | Clemson, S.C. | 6:30 PM | W, 9 - 4 | |
| home Wednesday, April 25 | Presbyterian | Clemson, S.C. | 6:30 PM | W, 14 - 4 | |
| away Friday, April 27 | Virginia * | Charlottesville, Va. | 6:00 PM | W, 3 - 2 | |
| away Saturday, April 28 | Virginia * | Charlottesville, Va. | 4:00 PM | W, 5 - 4 | |
| away Sunday, April 29 | Virginia * | Charlottesville, Va. | 1:00 PM | W, 9 - 8 | |
| home Saturday, May 05 | Florida State * | Clemson, S.C. | 6:30 PM | L, 2 - 3 (13) | |
| home Sunday, May 06 | Florida State * | Clemson, S.C. | 4:00 PM | W, 12 - 7 | |
| home Monday, May 07 | Florida State * | Clemson, S.C. | 7:00 PM | W, 5 - 4 | |
| home Wednesday, May 09 | Western Carolina | Clemson, S.C. | 6:30 PM | W, 10 - 8 | |
| home Friday, May 11 | Austin Peay | Clemson, S.C. | 6:30 PM | L, 3 - 6 | |
| home Saturday, May 12 | Austin Peay | Clemson, S.C. | 4:00 PM | W, 10 - 1 | |
| home Sunday, May 13 | Austin Peay | Clemson, S.C. | 1:00 PM | W, 3 - 2 (11) | |
| away Tuesday, May 15 | Kennesaw State | Kennesaw, Ga. | 6:00 PM | W, 7 - 2 | |
| away Thursday, May 17 | Pittsburgh * | Pittsburgh, Pa. | 6:00 PM | W, 16 - 6 | |
| away Friday, May 18 | Pittsburgh * | Pittsburgh, Pa. | 3:00 PM | W, 4 - 1 | |
| away Saturday, May 19 | Pittsburgh * | Pittsburgh, Pa. | 1:00 PM | W, 5 - 0 | |
| neutral Wednesday, May 23 | Notre Dame | ACC Tournament | Durham, N.C | 3:00 PM | W, 21 - 4 (7) | |
| neutral Thursday, May 24 | Miami | ACC Tournament | Durham, N.C | 7:00 PM | W, 7 - 1 | |
| neutral Saturday, May 26 | Florida State | ACC Tournament | Durham, N.C | 5:00 PM | L, 4 - 5 | |
| home Friday, June 01 | Morehead State | Clemson (S.C.) Regional | Clemson, S.C. | 7:00 PM | W, 4 - 3 (10) | |
| home Saturday, June 02 | Vanderbilt | Clemson (S.C.) Regional | Clemson, S.C. | 7:00 PM | L, 3 - 4 | |
| home Sunday, June 03 | St. John's | Clemson (S.C.) Regional | Clemson, S.C. | 12:00 PM | W, 9 - 8 | |
| home Sunday, June 03 | Vanderbilt | Clemson (S.C.) Regional | Clemson, S.C. | 6:00 PM | L, 6 - 19 | |
USC Upstate 
West Virginia 
Kentucky 
