| neutral Tuesday, August 09 | Ole Miss | Atlanta, Ga. | 7:00 PM | - | |
| home Sunday, August 14 | UNCW | Clemson, S.C. | 11:00 AM | - | |
| home Thursday, August 18 | Texas A&M | Clemson, S.C. | 7:00 PM | T, 0 - 0 | |
| home Sunday, August 21 | Campbell | Clemson, S.C. | 6:00 PM | W, 5 - 1 | |
| away Thursday, August 25 | Western Carolina | Cullowhee, N.C. | 7:00 PM | W , 6 - 0 | |
| away Sunday, August 28 | Alabama | Tuscaloosa, Ala. | 7:00 PM | L, 0 - 3 | |
| away Thursday, September 01 | #4 South Carolina | Columbia, S.C. | 7:00 PM | T, 2 - 2 | |
| home Sunday, September 04 | App State | Clemson, S.C. | 2:00 PM | W , 3 - 0 | |
| away Thursday, September 08 | #17 West Virginia | Morgantown, W. Va. | 7:00 PM | W , 1 - 0 | |
| home Thursday, September 15 | #6 Notre Dame * | Clemson, S.C. | 8:00 PM | W , 2 - 0 | |
| away Thursday, September 22 | Wake Forest * | Winston-Salem, N.C. | 8:00 PM | L, 1 - 4 | |
| away Sunday, September 25 | #7 Florida State * | Tallahassee, Fla. | 1:00 PM | L, 1 - 3 | |
| home Thursday, September 29 | NC State * | Clemson, S.C. | 8:00 PM | L, 1 - 2 | |
| away Thursday, October 06 | Louisville * | Louisville, Ky. | 7:00 PM | W , 2 - 1 | |
| home Sunday, October 09 | #24 Virginia Tech * | Clemson, S.C. | 1:00 PM | W, 2 - 1 | |
| away Friday, October 14 | Syracuse * | Syracuse. N.Y. | 7:00 PM | T, 1 - 1 | |
| home Thursday, October 20 | #10 Duke * | Clemson, S.C. | 7:00 PM | T, 0 - 0 | |
| home Sunday, October 23 | Boston College * | Clemson, S.C. | 1:00 PM | W, 3 - 0 | |
| away Thursday, October 27 | #24 Pittsburgh * | Pittsburgh, Pa. | 7:00 PM | T, 0 - 0 | |
| home Friday, November 11 | Vanderbilt | Clemson, S.C. | 3:00 PM | L, 0 - 1 | |
| home Thursday, March 02 | Georgia Southern | Clemson, S.C. | 7:30 PM | GO TIGERS | |
| home Sunday, March 12 | Charlotte | Clemson, S.C. | 4:00 PM | GO TIGERS | |
| away Monday, April 10 | Georgia | Athens, Ga. | 8:00 PM | GO TIGERS | |
| away Saturday, April 15 | North Carolina | Chapel Hill, N.C. | 1:00 PM | GO TIGERS | |
| home Saturday, April 22 | Tennessee | Clemson, S.C. | 1:00 PM | GO TIGERS | |
