Duke 
Florida State 
Louisville 
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South Carolina 
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Georgia Tech 
Syracuse 
North Carolina 
Boston College 
SMU 
Feb. 4, 2005
The Clemson Athletic Department has announced special dates for the 2005 football season. Among the designations is Homecoming, which will take place Nov. 5 against Duke. The date of the annual Clemson spring game has also been set for April 16 at 1:00 PM in Memorial Stadium.
| Date | Opponent | Designation |
| Sept. 3 | TEXAS A&M | Military Appreciation Day |
| Sept. 10 | at Maryland | |
| Sept. 17 | MIAMI | Hall of Fame/IPTAY Day |
| Sept. 24 | BOSTON COLLEGE | Family Weekend/One Clemson |
| Oct. 1 | at Wake Forest | |
| Oct. 13 | at NC State | |
| Oct. 22 | TEMPLE | Youth Day |
| Oct. 29 | at Georgia Tech | |
| Nov. 5 | DUKE | Homecoming |
| Nov. 12 | FLORIDA STATE | |
| Nov. 19 | at South Carolina | |
| All times TBA – Game Time FAQ |
