| away Saturday, August 10 | Charlotte | Charlotte, N.C. | 7:00 PM | | |
| home Tuesday, August 13 | Mobile | Clemson, S.C. | 7:00 PM | | |
| home Saturday, August 17 | Georgia State | Clemson, S.C. | 7:00 PM | | |
| home Thursday, August 22 | Penn State | Clemson, S.C. | 7:00 PM | W, 3 - 0 | |
| away Friday, August 30 | South Carolina | Columbia, S.C. | 7:00 PM | T, 2 - 2 | |
| home Friday, September 06 | Stanford * | Clemson, S.C. | 7:00 PM | L, 2 - 3 | |
| home Tuesday, September 10 | Loyola (Md.) | Clemson, S.C. | 7:00 PM | W, 6 - 0 | |
| away Friday, September 13 | Boston College * | Chestnut Hill, Mass. | 7:00 PM | W, 1 - 0 | |
| away Monday, September 16 | Holy Cross | Worcester, Mass. | 6:00 PM | T, 2 - 2 | |
| home Friday, September 20 | Wake Forest * | Clemson, S.C. | 7:30 PM | W, 1 - 0 | |
| home Tuesday, September 24 | Liberty | Clemson, S.C. | 7:00 PM | W, 1 - 0 | |
| away Friday, September 27 | Notre Dame * | South Bend, Ind. | 7:00 PM | L, 1 - 2 | |
| home Friday, October 04 | North Carolina * | Clemson, S.C. | 7:00 PM | W, 3 - 2 | |
| away Friday, October 11 | Louisville * | Louisville, Ky. | 8:00 PM | W, 3 - 2 | |
| home Tuesday, October 15 | Queens | Clemson, S.C. | 7:00 PM | W, 4 - 2 | |
| home Tuesday, October 22 | Upstate | Clemson, S.C. | 7:00 PM | W, 6 - 0 | |
| home Friday, October 25 | Syracuse * | Clemson, S.C. | 8:00 PM | W, 6 - 1 | |
| home Tuesday, October 29 | Wofford | Clemson, S.C. | 7:00 PM | W, 2 - 1 | |
| away Friday, November 01 | Virginia Tech * | Blacksburg, Va. | 6:00 PM | T, 2 - 2 | |
| home Wednesday, November 06 | Louisville | Clemson, S.C. | 6:00 PM | W, 3 - 1 | |
| home Sunday, November 10 | Stanford | Clemson, S.C. | 2:00 PM | W, 1 - 0 | |
| neutral Thursday, November 14 | Cal | Cary, N.C. | 8:00 PM | W, 3 - 2 | |
| neutral Sunday, November 17 | Wake Forest | Cary, N.C. | 12:00 PM | T, 1(6) - 1(7) | |
| home Sunday, November 24 | Providence | Clemson, S.C. (Historic Riggs Field) | 6:00 PM | W, 2 - 0 | |
| away Sunday, December 01 | Wake Forest | Winston-Salem, N.C. | 6:00 PM | L (OT), 1 - 2 | |
| away Saturday, February 22 | Atlanta United | Atlanta, GA | 2:00 PM | | |
| home Wednesday, February 26 | Greenville Triumph | Clemson, SC | 7:30 PM | | |
| away Saturday, March 01 | Charleston Battery | Charleston, SC | 6:00 PM | | |
| home Wednesday, March 26 | Furman | Clemson, SC | 7:30 PM | | |
| home Saturday, April 05 | College of Charleston | Clemson, SC | 2:00 PM | | |
