| home Saturday, August 12 | Coker | Clemson, S.C. | 7:00 PM | -- | |
| home Tuesday, August 15 | Furman | Clemson, S.C. | 7:00 PM | -- | |
| away Saturday, August 19 | Georgia State | Atlanta, Ga. | 7:00 PM | -- | |
| home Thursday, August 24 | UCF | Clemson, S.C. | 7:00 PM | L, 1 - 2 | |
| home Monday, August 28 | UNC Wilmington | Clemson, S.C. | 7:00 PM | T, 1 - 1 | |
| home Friday, September 01 | South Carolina | Clemson, S.C. | 7:00 PM | W, 2 - 0 | |
| home Tuesday, September 05 | Presbyterian | Clemson, S.C. | 7:00 PM | W, 6 - 0 | |
| away Saturday, September 09 | Notre Dame * | Notre Dame, Ind. | 7:00 PM | L, 2 - 3 | |
| away Tuesday, September 12 | USF | Tampa, Fla. | 7:00 PM | W, 3 - 2 | |
| home Friday, September 15 | Duke * | Clemson, S.C. | 7:30 PM | W, 2 - 0 | |
| home Tuesday, September 19 | Gardner-Webb | Clemson, S.C. | 7:00 PM | W, 7 - 0 | |
| away Friday, September 22 | Wake Forest * | Winston Salem, N.C. | 6:00 PM | L, 0 - 1 | |
| home Friday, September 29 | Virginia Tech * | Clemson, S.C. | 7:00 PM | W, 2 - 1 | |
| home Tuesday, October 03 | Winthrop | Clemson, S.C. | 7:00 PM | W, 4 - 1 | |
| home Friday, October 06 | Louisville * | Clemson, S.C. | 7:00 PM | W, 4 - 0 | |
| away Sunday, October 15 | Syracuse * | Syracuse, N.Y. | 1:00 PM | T, 1 - 1 | |
| home Friday, October 20 | Boston College * | Clemson, S.C. | 6:00 PM | W, 6 - 0 | |
| away Friday, October 27 | NC State * | Raleigh, N.C. | 7:00 PM | T, 1 - 1 | |
| home Sunday, November 05 | Duke | Clemson, S.C. | 6:00 PM | T, 3(4) - 3(1) | |
| home Wednesday, November 08 | Cardinals | Clemson, S.C. | 8:00 PM | W, 5 - 1 | |
| neutral Sunday, November 12 | Tar Heels | Cary, N.C. | 12:00 PM | T, 1(5) - 1(3) | |
| home Sunday, November 19 | Charlotte | Clemson, S.C. (Historic Riggs Field) | 6:30 PM | W, 3 - 0 | |
| away Sunday, November 26 | New Hampshire | Durham, N.H. | 5:00 PM | W, 1 - 0 | |
| home Saturday, December 02 | Stanford | Clemson, S.C. (Historic Riggs Field) | 6:00 PM | W, 2 - 0 | |
| neutral Friday, December 08 | West Virginia | Louisville, Ky. | 6:00 PM | W, 1 - 0 | |
| neutral Monday, December 11 | Notre Dame | Louisville, Ky. | 6:00 PM | W, 2 - 1 | |
| home Saturday, February 24 | NC State | Clemson, S.C. | 2:00 PM | | |
| home Saturday, March 02 | Duke | Clemson, S.C. | 3:00 PM | | |
| home Tuesday, March 05 | Crown Legacy FC | Clemson, S.C. | 6:00 PM | | |
| away Sunday, April 07 | Virginia Tech | Blacksburg, V.A. | 1:00 PM | | |
| away Sunday, April 14 | Spring Soccer Cup | Winston-Salem, N.C. | ALL DAY | | |
