| home Wednesday, November 10 | Upstate | Clemson, S.C. (Littlejohn Coliseum) | 7:00 PM | W, 64 - 47 | |
| home Sunday, November 14 | Columbia | Clemson, S.C. (Littlejohn Coliseum) | 12:00 PM | L, 78 - 82 | |
| away Wednesday, November 17 | #1/1 South Carolina | Columbia, S.C. (Colonial Life Arena) | 7:00 PM | L, 45 - 76 | |
| home Sunday, November 21 | Penn State | Clemson, S.C. (Littlejohn Coliseum) | 2:00 PM | W, 67 - 64 | |
| home Wednesday, November 24 | North Florida | Clemson, S.C. (Littlejohn Coliseum) | 1:00 PM | W, 84 - 72 | |
| home Sunday, November 28 | Mount St. Mary's | Clemson, S.C. (Littlejohn Coliseum) | 2:00 PM | W, 83 - 59 | |
| home Thursday, December 02 | Northwestern | Clemson, S.C. (Littlejohn Coliseum) | 8:00 PM | L, 61 - 72 | |
| home Sunday, December 05 | Presbyterian College | Clemson, S.C. (Littlejohn Coliseum) | 2:00 PM | W, 48 - 42 | |
| away Saturday, December 11 | Syracuse * | Syracuse, N.Y. | 6:00 PM | L, 46 - 86 | |
| home Friday, December 17 | Wofford | Clemson, S.C. (Littlejohn Coliseum) | 7:00 PM | W, 84 - 49 | |
| neutral Monday, December 20 | LSU | West Palm Beach, Fla. | 5:45 PM | L, 56 - 70 | |
| neutral Tuesday, December 21 | Dayton | West Palm Beach, Fla. | 3:30 PM | L, 46 - 60 | |
| home Thursday, December 30 | NC State * | Clemson, S.C. (Littlejohn Coliseum) | 7:00 PM | L, 52 - 79 | |
| away Sunday, January 02 | North Carolina * | Chapel Hill, N.C. | 6:00 PM | L, 62 - 81 | |
| away Thursday, January 06 | Florida State * | Tallahassee, Fla. | 6:00 PM | POSTPONED | |
| home Sunday, January 09 | Boston College * | Clemson, S.C. (Littlejohn Coliseum) | 12:00 PM | L, 74 - 80 | |
| home Thursday, January 13 | Miami * | Clemson, S.C. (Littlejohn Coliseum) | 7:00 PM | L, 60 - 69 | |
| away Sunday, January 16 | Virginia Tech * | Blacksburg, Va. | 6:00 PM | POSTPONED | |
| home Tuesday, January 18 | Florida State * | Clemson, S.C. (Littlejohn Coliseum) | 6:00 PM | L, 68 - 79 | |
| away Thursday, January 20 | Wake Forest * | Winston-Salem, N.C. | 7:00 PM | W, 66 - 44 | |
| away Sunday, January 23 | Florida State * | Tallahassee, Fla. | 2:00 PM | L, 70 - 75 | |
| home Thursday, January 27 | Pitt * | Clemson, S.C. (Littlejohn Coliseum) | 7:00 PM | L (OT), 73 - 78 | |
| home Sunday, January 30 | Georgia Tech * | Clemson, S.C. (Littlejohn Coliseum) | 6:00 PM | L, 62 - 69 | |
| home Thursday, February 03 | Louisville * | Clemson, S.C. (Littlejohn Coliseum) | 6:00 PM | L, 71 - 93 | |
| away Sunday, February 06 | Virginia * | Charlottesville, Va. | 4:00 PM | W, 59 - 55 | |
| away Tuesday, February 08 | Virginia Tech * | Blacksburg, Va. | 6:00 PM | L, 42 - 73 | |
| home Thursday, February 10 | Wake Forest * | Clemson, S.C. (Littlejohn Coliseum) | 2:00 PM | W, 87 - 78 | |
| away Sunday, February 13 | Georgia Tech * | Atlanta, Ga. | 12:00 PM | L (OT), 84 - 92 | |
| home Sunday, February 20 | Duke * | Clemson, S.C. (Littlejohn Coliseum) | 2:00 PM | L, 61 - 64 | |
| away Thursday, February 24 | Notre Dame * | Note Dame, Ind. | 8:00 PM | L, 56 - 77 | |
| away Sunday, February 27 | Miami * | Miami, Fla. | 4:30 PM | L, 40 - 76 | |
| neutral Wednesday, March 02 | Syracuse | Greensboro, N.C. | 1:00 PM | W, 88 - 69 | |
| neutral Thursday, March 03 | Virginia Tech | Greensboro, N.C. | 11:00 AM | L, 60 - 82 | |
